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Idris, S., Mishra, A
Selectivity validation using GSH-depleted controls (e.g., buthionine sulfoximine [BSO]-treated cells) is a standard practice in well-designed preclinical studies
Reactivity of phospholipid hydroperoxide glutathione-peroxidase with membrane and lipoprotein lipid hydroperoxides
Review the evidence, understand the mechanism, and explore peptide alternatives that avoid this pro-angiogenic signal
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