Lamellar Architecture Tuning: Customizing the vesicle structure from Multi-Lamellar Vesicles (MLV) for sustained, depot-like release to Small Uni-Lamellar Vesicles (SUV) for rapid, deep-tissue permeation
The liquid form or the lyophilizate powder form of the composition of the present invention may be dissolved or dispersed in a solution of a biodegradable polymer such as poly(lactic-glycolic) acid copolymer, poly(hydroxybutyric acid), poly(hydroxybutyric-glycolic) acid copolymer, or the mixture of these, and then may be formulated, for example, to films, microcapsules (microspheres), or nanocapsules (nanospheres), particularly in the form of soft or hard capsules
The effectiveness often depends on factors like the person's skin type, the dosage used, and how frequently the injections are administered
Unlike propranolol, only a small portion of atenolol is apparently distributed into the CNS