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Finally, evaluate combinations with dietary interventions and orthogonal metabolic agents to delineate additivity versus redundancy within energy-balance networks

Gut symptoms may involve motility, inflammation, infection, immune reactions, microbiome changes, or medication effects

Identifying additional biomarkers that robustly correlate with esophageal carcinogenesis, progression, and treatment response, as well as characterizing neoantigens and other mechanisms to induce or maintain antitumor immune responses, is essential for improving EC management

However, theres currently no evidence that taking B12 supplements increases energy levels in people who are not deficient in this nutrient