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Thirdly, protein restriction in humans (283) and rodents (84), particularly with concomitant high-carbohydrate dietary content (284), increases circulating FGF21
If CagriSema truly prevents the metabolic slowdown associated with weight loss, as the preclinical data suggests, it could produce more durable outcomes with less weight regain after treatment completion
There were several factors varying between our patient and the other cases, particularly our patient also taking an SGLT2 inhibitor, but our case may suggest greater risk of EKA for a patient on synergistic regimens, Louwagie says
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