tirzepatide vs dulaglutide demonstrates cardiovascular protection in head-to-head trial with Cardiovascular outcomes of semaglutide and

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The evidence base is almost entirely preclinical: rodent models consistently show accelerated tissue repair, gut healing, and neurological protection, but human RCT data remains largely absent

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Highlights: GLP-1 receptor agonists were associated with a slightly higher relative risk of nonarteritic anterior ischemic optic neuropathy (NAION) , although the one-year absolute risk remained only 0.04% A nationwide Swedish cohort study followed more than 293,000 adults with type 2 diabetes who started GLP-1 receptor agonists or SGLT-2 inhibitors