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10.1056/NEJMe2202547 N Engl J Med

Table 1 Current clinical trials of myostatin signaling pathway inhibitors, alone or in combination with glucagon-like peptide-1 agonists, in metabolic disorders REFERENCES 1

An increase in dose intensifies these effects, worsening gastrointestinal side effects such as nausea, diarrhea, constipation, and abdominal pain

*Correspondence: Yi Hua, [email protected] This article was submitted to Experimental Pharmacology and Drug Discovery, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers