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When B12 levels drop, the resulting drop in SAMe leads to the hypomethylation of myelin basic protein

Targeting Malignant Brain Tumors with Antibodies

This does not affect reconstitution, but it means the mechanism of action differs

In a dissenting comment, Sikiric and colleagues said that BPC-157 had been unjustly accused of potentially harmful effects. They pointed to a list of research findings that, in their view, rule out the possibility that the peptide causes cancer and other potential harms