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About one in five patients taking semaglutide in SELECT had to stop treatment
For health systems, this means navigating new financial risk, negotiating value-based arrangements and preparing for changes in reimbursement
Any cloudiness may indicate aggregation or microbial contamination Visible particles or floaters particulate matter suspended in the solution is a clear sign of degradation or contamination Discolouration yellowing or browning of the solution suggests oxidative degradation of amino acid residues Gel-like or viscous consistency peptide aggregation can occasionally produce a thickened solution Compromised vial or packaging integrity any damage to the vial, stopper, or seal is grounds for immediate discard Beyond visual inspection, time elapsed since reconstitution is itself a critical consideration
Safety issues of Tirzepatide (pancreatitis and gallbladder or biliary disease) in type 2 diabetes and obesity: a systematic review and meta-analysis
