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The stratum corneum, the outer layer of skin, is a lipophilic barrier designed to keep hydrophilic molecules out
Examples include: Insulin regulates blood sugar in diabetes GLP-1 medications (semaglutide, tirzepatide) used for diabetes and weight management Calcitonin used in bone metabolism disorders These medications underwent years of clinical trials and regulatory review before becoming approved treatments
Cardiolipin: a proton trap for oxidative phosphorylation
Galluzzi L, Bravo-San Pedro JM, Vitale I, Aaronson SA, Abrams JM, Adam D, et al
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