Sleep Quality: As mentioned, sleep is when your body naturally replenishes its antioxidant stores

Now fill out the AE document Lets fill out the AE Page Subject: 99-045 Event: Migraine Onset Date: 31-MAY-2005 Resolution Date: 1-JUN-2005 Severity: Relation to Study Drug: Action Taken: Medication (Excedrin Migraine) Outcome: Recovered Serious: NO Concomitant Medications All medications need to be recorded (including, supplements, vitamins and topical medications) Get as much information (dose, route, frequency etc) as you can the first time Make sure that AE form is completed if the conmed indication was an AE Lets fill out the Con Meds Source Page Medication: Excedrin Migraine Dosage: 2 Tablets Administration Route: Oral Frequency: Every 8 hours Indication: Migraine Date Started: May 31st, 2005 Date Stopped: June 1st, 2005 Helpful Hints If a medication changes, ask why, the underlying cause may need to be recorded as an adverse event Document Reasons for all missed visits or out of window visits These may be due to an AE that may need to be recorded Overall Some Helpful Hints KEEP ALL STUDY RELATED DOCUMENTS Even if they seem outdated file in the regulatory binder or in patient binders Write EVERYTHING down, before you forget Put subject numbers on every piece of paper So you know which subject it belongs to Address all issues in your monitor follow up letters ASAP Initial and date everything When in doubt initial and date anyway

Water, Butylene Glycol, Glycerin, 1.2-Hexanediol, Niacinamide, Hydroxy ethyl Urea, Maltodextrin, Arginine, Glutathione, C12-14Alketh-12, Diospy ros Kaki Fruit Extract, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Cetyl Ethylhexanoate, Ethylhexyl Palmitate, Hydrogenated Polydecene, Macada mia Ternifolia Seed Oil, Squalane, Juniperus Mexicana Oil, Polyglyceryl-2 Stearate, Adenosine, Polyglyceryl-10 Laurate, Phytosteryl/Behenyl/Octyldo decyl Lauroyl Glutamate, Cholesterol, Brassica Campestris (Rapeseed) Ste rols, Glyceryl Stearate, Carbomer, Abies Sibirica Oil, Elettaria Cardamomum Seed Oil, Vetiveria Zizanoides Root Oil, Stearyl Alcohol, Hydrogenated Le cithin, PVM/MA Copolymer, Vinyl Dimethicone, Dipropylene Glycol, Hydro xyacetophenone, Sodium Hyaluronate, Polyglutamic Acid, Hydroxyethyl cellulose, Ceramide NP, Stearic Acid, Tocopherol, Oleic Acid, Disodium EDTA, Caprylyl Glycol, Ethylhexylglycerin, Ascorbic Acid, Retinyl Palmitate, Riboflavin, Pantothenic Acid, Niacin, Folic Acid, Thiamine HCI, Carnitine HCI, Biotin, Phosphatidylcholine, Manganese Sulfate, Magnesium Sulfate

Question: Can this supplement be taken with or without meals