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GLP-1 receptor expression is reduced in circulating peripheral blood mononuclear cells (PBMCs) from chronic obstructive pulmonary disease (COPD) patients as compared to non-COPD controls [73]
GSH is synthesized from cysteine, glutamate, and glycine by the ATP-dependent enzyme -glutamyl-cysteine (-GC) ligase (GCL) synthetase, which is composed of the -GC ligase catalytic subunit (GCLC), the -GC modifier subunit (GCLM), and GSH synthetase (GSS) 24
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