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eLife 10 , e65935 (2021)
Chen X, Zhang J, Zhou Z
Unlike growth hormone therapies that stimulate pituitary secretion, IGF-1 LR3 directly activates cellular growth and repair pathways
Research applications Research applications In vitro GHRH receptor and GHSR (ghrelin receptor) binding and signaling assays cAMP/PKA pathway and somatotroph activation studies Cellular secretion and endocrine axis modeling Mechanistic combination and dose-response interaction studies For laboratory research use only
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