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Eating smaller, more frequent mealsrather than large portionsreduces the feeling of stomach fullness that can amplify nausea when the medication is slowing digestion

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These dangers are amplified in certain high-risk populations, including those with a history of diabetic ketoacidosis, poor diabetes control, chronic kidney disease, and liver disease

Useful oxidative-damage markers may include urinary 8-OHdG , which reflects oxidative DNA damage, and lipid peroxides , which reflect oxidative damage to fats and cell membranes