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Wu , Michael Snyder Stanford Cardiovascular Institute #Longevity #Metformin #Omega3 #Exercise #Apelin #MetabolicHealth C-Level Biopharma Executive & Entrepreneur | Advisor in Formulation Development/CMC & Drug Delivery | Translational Drug Development Key Findings of A Major Diabetes Clinical Trial: - No Direct Reversal: After 26 weeks, metformin failed to improve insulin resistance in the liver, muscle, or adipose (fat) tissues of adults with Type 1 diabetes
A few notable mechanisms include improving insulin secretion, suppressing appetite, and delaying gastric emptying
Despite promising preliminary findings, these compounds are generally associated with a poor spatial and temporal control of the treatment as well as poor cancer selectivity, resulting in potential side effects and non-ideal drug doses
doi:10.3390/genes12071093
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