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Patients experiencing these symptoms should discontinue their GLP-1 medication immediately and seek urgent medical evaluation
E.et al (2018)
In a study involving rats, prednisolone, a glucocorticoid, was found to increase the hepatic capacity for urea-N synthesis (CUNS) and elevate the expression of urea cycle genes, which contributes to nitrogen loss
Understanding these contributing mechanisms enables healthcare providers to implement targeted management strategies, optimize treatment tolerability, and distinguish medication-related fatigue from potentially serious underlying conditions requiring further evaluation
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