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The amount of copper in topical GHK-Cu products is far too small to cause systemic copper toxicity
in the placebo group, the mean systolic blood pressure decreased to 133.5 mm Hg and 132.8 mm Hg, for reductions of 2.2 mm Hg and 2.8 mm Hg, respectively
We already know the short-term side effects that patients taking these drugs to lose weight have experienced: nausea, vomiting, bloating, and some more extreme (albeit rare) things like bowel obstruction, pancreatitis, and stomach paralysis
In patients with HFpEF and obesity, both semaglutide (STEP-HFpEF) and tirzepatide (SUMMIT) significantly reduced cardiovascular death and worsening heart failure events, with concomitant improvements in quality of life and functional capacity [3,47]
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