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Important considerations include: GLP-1 agonists are generally well-tolerated in people with hypertension They do not typically cause dangerous drops in blood pressure Dehydration from gastrointestinal side effects (nausea, vomiting, diarrhoea) can occasionally affect blood pressure and kidney function, so maintaining adequate fluid intake is important If you take diuretics (water tablets), ACE inhibitors or ARBs for blood pressure, your doctor may monitor you more closely during the initial weeks of GLP-1 therapy Seek medical advice promptly if you experience persistent gastrointestinal symptoms that prevent adequate fluid intake NICE guidance (NG28) supports the use of GLP-1 agonists in people with type 2 diabetes who meet specific criteria, with preference for agents with proven cardiovascular benefits in those with established cardiovascular disease

Q: What is the primary difference between Semaglutide and Tirzepatide

If you have been told that the fat around your midsection is cortisol belly fat or a hormonal belly, you have probably seen a lot of advice online that promises to get rid of it with a supplement or a special morning routine

Retatrutide referenced in this article is discussed in its current investigational context