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The good news: cramping typically subsides as your body adapts to the medication and reaches a new equilibrium

In one published case, an active, lean-adjacent man lost about one-third of his total weight as muscle on 2.5 mg and recovered it after adding resistance training and increasing protein. This is a cautionary case, not an incidence estimate

[1] [2] Administered as a once-weekly subcutaneous injection, it works by mimicking the action of the naturally occurring hormone GLP-1, which stimulates insulin secretion in response to elevated blood glucose levels, suppresses glucagon release, and slows gastric emptying

It is also FDA approved for cardiovascular risk reduction (to lower the risk of heart attack, stroke, and cardiovascular death) in people with both Type 2 diabetes and heart disease