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Impaired mitochondrial metabolism reduces ATP synthesis, thereby impairing cardiac and renal function ( 2.3 Endoplasmic reticulum and oxidative stress modulation Endoplasmic reticulum stress (ERS), triggered by hypoxia, calcium dyshomeostasis, or autophagic impairment, disrupts the nitric oxide/reactive oxygen species (NO/ROS) balance, thereby activating cascades implicated in cardiovascular disease and diabetes

After 48 h, cells were transfected with GFP-fusion constructs, and 24 h later cells were fixed and immunostained against GM130

Dec 22 2022;13(6):2357-2405

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