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If you have a vitamin B12 deficiency, you may experience a range of symptoms, including fatigue and weakness, shortness of breath, pale skin, headaches, dizziness, numbness or tingling in hands and feet, digestive issues like diarrhoea or constipation, mood changes like depression or anxiety, and memory loss or cognitive impairment

However, its use has been supplanted by better-tolerated agents because of concerns regarding numerous adverse side effects (listed below)

PMID: 23240940

The resolution of joint inflammation could inhibit inflammatory cytokines-induced osteoclast activation and facilitate the remission of bone erosion