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But certainly in patients who may have a greater level of obesity associated with their type 2 diabetes, perhaps initiating semaglutide before an SGLT2 inhibitor because of the weight benefit, the CV risk lowering, as well as the CKD benefit, may be appropriate. More screening needed Providers are hopeful the FLOW trial may raise greater awareness of CKD screening, particularly the measurement of UACR

Here is how a clinic thinks about it, peptide by peptide

Combining the two creates comprehensive 24-hour glucose coverage

ROS can modify contractile proteins such as actin and myosin, reducing their functionality and contributing to decreased muscle performance