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Identifying metabolic imbalances can guide targeted interventions to optimize health and vitality

The biology that once defended obesity reasserts itself with remarkable speed, exposing the central paradox of the GLP-1 era: medicine has learned how to drive weight loss, but not how to maintain it

FIGURE 5 3.6 Impact of remogliflozin on the Nrf2 pathway in TAA-intoxicated rats Compared to the control group, TAA significantly suppressed the Nrf2 pathway by reducing Nrf2 protein and gene expressions by 62.7% and 53.8%, respectively

This may be attributed to an insufficient degree of mitophagy enhancement to effectively clear damaged mitochondria