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Substances in Category 2 (deemed to have safety risks) and Category 3 (deemed to have insufficient evidence for FDA evaluation) may not be compounded

Its also approved to reduce serious cardiovascular risks in certain adults and manage metabolic dysfunction-associated steatohepatitis (MASH)

American College of Cardiology Expert Consensus Decision Pathway on Novel Therapies for Cardiovascular Risk Reduction in Patients with T2D and Atherosclerotic Cardiovascular Disease In 2018, the American College of Cardiology (ACC) published an expert consensus decision pathway on the use of novel therapies, namely GLP-1 RAs and SGLT-2 inhibitors, to reduce cardiovascular risk in patients with T2D

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