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Lastly, we tested whether cells that were functionally deficient in mitochondrial ETC metabolism, owing to mutations in CI and CIV, were differentially sensitive to 5FU treatment
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The culture medium was then removed after 24 hours incubation
Mitochondria are composed of a double lipid bilayer with a permeable phospholipid outer membrane and an impermeable phospholipid inner membrane that surrounds the intra-compartmental matrix
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