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Underlying principles and operating procedures DCE is one of the most widely used MRI techniques to assess BBB permeability by examining leakage of contrast agents into the brain parenchyma
In 2024-25, just 10 medicines accounted for 30 per cent of all spending on over co-payment PBS medicines, with six of these medicines averaging more than $1,000 per dispense: Department of Health, Disability, and Ageing (2026a, Tables 3a and 5a)
The therapeutic value of this approach lies in its capacity to encourage the formation of new functional synaptic connections among existing neurons, encourage the replacement of damaged and lost neurons from available neural stem cell populations, and facilitate cerebral blood flow and neuroprotection
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