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For example, fisetin acts through multimodal mechanisms by targeting key regulators such as the PI3K/AKT, BCL-2, p53 and NF-B signaling pathways (208)

FOXO4 protein is a prominent member of the group of transcription factors classified as exhibiting potential to regulate growth and differentiation

Frailty A medical and geriatric syndrome characterized by a decline in physiological reserves and increased vulnerability to stressors, leading to an increased risk of adverse health outcomes