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Apart from improvements in multiple cardiometabolic risk factors, tirzepatide also improves various obesity-related complications such as obstructive sleep apnoea (OSA), metabolic dysfunction-associated steatohepatitis (MASH) and heart failure with preserved ejection fraction [28,29,30]
It is important to highlight that the signal associated with PER exhibited a considerable level of stability and significance, remaining unaffected by VPA
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