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In vivo studies in volunteers with atopic and dry skin showed no irritation or intolerance

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The best powered of these studies examined genetic variation in 42 genes (308 single nucleotide polymorphisms (SNPs)) related to glutathione, including those coding for enzymes that use glutathione as a co-factor (not included in this review), in 318 families from the Autism Genetic Resource Exchange repository [87]

As of now, here is what we know so far: 1