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Related studies mainly focus on in vivo intervention efficacy validation, exploration of combined intervention strategies, and optimization of pharmaceutical dosage forms, providing important experimental evidence for clinical intervention of obesity

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Experimental study demonstrates that LDN induces a phenotypic shift in BV-2 microglial cells, transitioning them from a pro-inflammatory(iNOS high CD206 low ) to a quiescent, anti-inflammatory M2 state (iNOS low CD206 high ) [150]

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