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Track energy levels, as some patients report fatigue during initial treatment or dose escalation

For example, in the SURMOUNT-1 trial, approximately 75% of the weight lost was fat mass and 25% was lean mass

Semaglutide works by activating GLP-1 receptors in the brain and digestive system to reduce hunger and slow stomach emptying, but this mechanism occurs alongside whatever thyroid-related metabolic state you already have

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