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For observational studies (cohort and case-control), the NewcastleOttawa Scale (NOS) ( Risk of bias was interpreted as follows: i) Low risk: All criteria met or no more than one rated as unclear
J Neurol
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Reasons for overdiagnosis A recent UK study examining diagnostic testing rates in general practice between 2000 and 2015 highlighted a significant linear (around 17% annually) increase in vitamin B12 requests 5
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