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The TRIUMPH programme is evaluating retatrutide across multiple indications including chronic weight management, type 2 diabetes, knee osteoarthritis, moderate-to-severe obstructive sleep apnoea, chronic low back pain, cardiovascular and renal outcomes, and MASLD
This included 28,430 cardiovascular deaths (103 per 100,000 person-years), 83,489 nonfatal myocardial infarctions (303 per 100,000 person-years), and 24,521 nonfatal strokes (89 per 100,000 person-years), with a number needed to treat (NNT) of 55 for MACE
If digestive symptoms continue while using weight loss medication, Mayfair Weight Loss Clinic can help you review your concerns and understand the next steps with appropriate clinical guidance
Although the anti-obesity mechanisms of BBR have been well-characterized in preclinical models with demonstrated efficacy, critical limitations persist in current research paradigms
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