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Such as this 2000 study done in obese rats: Daily treatment with an oral dose of AOD9604 of 500 g/kg body weight for 19 days reduced over 50% (15.8 0.6 vs
In a subsequent study, lean Gipr AP-KO and Gipr AP-GFP mice were switched to an HFD on the same day as initiating 10 days of daily injections with either LIRA (or VEH) alone, or LIRA (or VEH) plus GIPR antagonist peptide (GIPR-antag) 6
Most users eventually establish a sustainable pattern: perhaps 4-6 weeks of active use followed by 2-3 weeks off, repeated as needed based on sleep quality and life demands
My hunger has gone down and I feel fuller after eating less
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