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NICE guidance on obesity management (CG189) emphasises evidence-based interventions including dietary modification, increased physical activity, behavioural therapy, andwhere appropriatepharmacotherapy with licensed medications such as orlistat or semaglutide (NICE TA875)
Tests include the leading-standard techniques of Mass Spectrometry and High-Performance Liquid Chromatography (HPLC), the most accurate methods available
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Semaglutide and Kidneys : While semaglutide itself is not directly harmful to the kidneys, its side effects like nausea, vomiting, and diarrhea can lead to dehydration, which may indirectly strain the kidneys
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