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ESC functions as an antioxidant through dual mechanisms: direct ROS scavenging via hydroxyl groups at positions 6 and 7 of the coumarin ring, which donate electrons to ROS, converting them to inert products, and indirect antioxidant upregulation via Nrf2/ARE pathway activation
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Dassanayake TL, Kahathuduwa CN, Weerasinghe VS
Angle the needle against the inside wall of the vial and depress the plunger slowly
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