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At non-toxic concentrations of 1 to 10 nM, the peptide stimulates in preclinical models both the synthesis and the breakdown of collagen and glycosaminoglycans such as dermatan and chondroitin sulfate as well as decorin, and it modulates matrix metalloproteinases together with their inhibitors TIMP-1 and TIMP-2

Advanced Bioregulator for Longevity and Cellular Studies Epitalon (Epithalon) is a synthetic tetrapeptide bioregulator studied for its potential effects on telomerase activity and cellular aging mechanisms