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18 The treatment protocol for TPE consists of removing and retaining a considerable volume of plasma, approximately 1 to 1.5 plasma volume, 17 and returning the necessary cellular components via a colloid or combination colloid/crystallization solution of either fresh frozen plasma (FFP) or albumin

Zaffanello, M., et al

Oral administration demonstrates activity in gastrointestinal conditions despite lower systemic bioavailability, as direct mucosal exposure may contribute to therapeutic effects