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In one semaglutide analysis, 32% of people achieved less than 5% loss from baseline or gained weight, while 5% lost more than 25%
Three models were constructed: Model 1 (crude model), Model 2 (adjusted for age and sex), and Model 3 (fully adjusted for potential confounders including BMI, blood pressure, lipid profile, renal function, osteocalcin (OCN), vitamin D levels, HbA1c, statin use, antihypertensive medication use, and smoking status)
This is typically a localized skin reaction and does not necessarily indicate an internal issue
Diabetes Obes Metab (2020) 22:44251
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