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A meta-analysis of 8 RCTs found that NAC supplementation significantly reduced fasting glucose (WMD: -5.84 mg/dL) and HbA1c (WMD: -0.27%) in people with metabolic conditions (Sarkaki et al., Clin Nutr ESPEN, 2021) [57]
A 2024 review documented studies across gastric, intestinal, musculoskeletal, vascular, neural, and dermal tissue (PMID 38980576)
Peled and colleagues, members of a stem cell biotech firm (Gamida Cell, Jerusalem, Israel), has claimed, in a patent, that GHK increases proliferation of stem cells, while GHK-Cu increases their progression into differentiated cells [ 40 ]
There are also classes of GSTs that utilize glutathione as a cofactor rather than a substrate
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