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This finding is particularly relevant when considering GLP-1 medications, because these drugs often produce substantial weight reduction
They are medical therapies that require medical guidance
Hunger persistence on semaglutide often reflects underdosing, genetic variation in GLP-1 receptor sensitivity, or psychological/emotional eating patterns unrelated to physical appetite
Medication is intended to be used as part of a comprehensive treatment plan that includes nutrition, physical activity, and lifestyle modification when appropriate
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