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They're methyl donors and mitochondrial cofactors
A sub-study of the randomized phase 3 SURPASS-3 trial evaluated the changes in liver fat content (LFC), abdominal subcutaneous adipose tissue (ASAT), and volume of visceral adipose tissue (VAT) in patients treated with tirzepatide compared to patients treated with insulin degludec
Regulatory Science , 8
Ongoing monitoring should be individualised based on symptoms and risk factors, with repeat testing at 3-6 month intervals for those at higher risk
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