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Ovarian granulosa cells regulate the accumulation of serotonin in oocytes through the uptake and degradation of serotonin by SERT and monoamine oxidase (MAO), respectively, and granulosa cells form a functional barrier that protects oocytes from exogenous serotonin and may play an important role in oocyte maturation and early embryonic development (Figure 3)
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Additional studies are needed to clarify the mechanisms involved and to improve LipRSV treatment approaches
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