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You can limit your chances of an acid reflux episode by not eating late at night and avoiding fatty foods, both of which can loosen the lower esophageal sphincter, Rothstein says
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In terms of appetite suppression onset, many patients report that tirzepatide produces noticeable effects slightly faster, likely due to its dual GIP/GLP-1 mechanism
Semaglutide is a synthetic medication engineered to mimic GLP-1's effects while remaining active for approximately 7 days, enabling practical once-weekly dosing
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