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Additionally, disruptions in the blood-brain barrier in those with neurocognitive symptoms have been observed, as well as hypoperfusion in various organs, contributing to end-organ dysfunction [364, 365]
Veterinary dermatology , 19 (1), 714
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PubMed Research indicates that retinoids including retinol remain the gold standard for topical anti-aging treatments, though their application is frequently limited by skin irritation and poor tolerability, particularly in sensitive or aged populations
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