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125 This protective mechanism is likely facilitated through the activation of the adenosine 5-monophosphateactivated protein kinase (AMPK) pathway, which plays a crucial role in managing cellular stress and the DNA repair process
In February, based on early results of promising anti-tumor activity and manageable safety profile from a Phase I study, the FDA granted Fast Track Designation to CUSP06, a Cadherin-6 ADC employing exatecan as the payload, for the treatment of PROC
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ALCAR, in particular, has been shown to stabilize cardiolipin, the crucial lipid that anchors the mitochondrial membrane
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