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For medical applications, copper intrauterine devices are a type of long-acting contraceptive because copper (II) ions released from the devices are deleterious to sperm cells 1

As a result, clinicians face both new opportunities and serious risks in maintaining continuity of care

and Eli Lilly, the maker of tirzepatide, the active ingredient in Zepbound, warn about medications claiming to be the compounded versions of brand-name GLP-1 weight-loss drugs

Neuropsychiatric reactions including suicidal thoughts have been reported with GLP analogs, although barely exceeding placebo and unlikely to warrant clinical concern (O'Neil et al, 2017)