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I only apply the patch once a week, and the process is easy and there is no discomfort, but the effect is unexpectedly obvious

If genetic testing reveals that you have variants associated with heightened GI sensitivity, your provider can recommend a more conservative dose escalation, additional reflux prevention strategies, or even a trial of oral semaglutidean alternative form that may trigger less acute gastric effects than injections

Kozicure cream for local application is advised for 3-6 weeks , at bedtime ,if any side-effects dermat opinion is advised

Side effects typically diminish after the first week as receptor tolerance develops