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Often referred to as an exercise mimetic in preclinical research, SLU-PP-332 has gained significant interest within the scientific community due to its interaction with estrogen-related receptors (ERRs), which play a role in cellular energy production and mitochondrial function
This finding highlights a fundamental distinction that must be applied when interpreting the preclinical literature as a whole: the majority of studies reporting positive outcomes employed a preventive or co-treatment paradigm, in which the drug was administered prior to or concurrently with pathological induction
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