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Moreover, emerging mechanistic and clinical evidence published in recent years has not yet been comprehensively integrated

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Conflict of interest SW reports receiving grants from Novo Nordisk, speaking engagement fees from Bausch and Lomb, Eli Lilly and Company, Novo Nordisk, advisory board fees from Biohaven Pharmaceuticals, Inc., Boehringer Ingelheim, Eli Lilly and Company, Novo Nordisk

Strikingly, the study revealed that the immune cells of these patients act as an "energy sink." In a desperate attempt to survive the overwhelming oxidative stress, the immune cells upregulate their own intracellular glutathione production