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Also, the incidences of thrombotic events increase with age
In short: its not just in your head
5 While its primary endpoint (a composite including all-cause mortality, nonfatal MI, stroke, acute coronary syndrome, leg revascularization, and major leg amputation) did not reach significance, a main secondary composite endpoint (all-cause mortality, nonfatal MI, and stroke) showed a significant benefit with pioglitazone (hazard ratio [HR] 0.84
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Brains were collected, post-fixed in 4 C PFA 4% overnight and cryoprotected in sucrose 30% for 23 days
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